Deep brain stimulation can preserve working status in Parkinson's disease

Gabriella Deli, István Balás, Tamás Dóczi, József Janszky, Kázmér Karádi, Zsuzsanna Aschermann, Ferenc Nagy, Attila Makkos, Márton Kovács, Edit Bosnyák, Norbert Kovács, Sámuel Komoly

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11 Citations (Scopus)


Objectives. Our investigation aimed at evaluating if bilateral subthalamic deep brain stimulation (DBS) could preserve working capability in Parkinson's disease (PD). Materials. We reviewed the data of 40 young (<60 year-old) PD patients who underwent DBS implantation and had at least 2 years of follow-up. Patients were categorized based on their working capability at time of surgery: "active job" group (n=20) and "no job" group (n=20). Baseline characteristics were comparable. Quality of life (EQ-5D) and presence of active job were evaluated preoperatively and 2 years postoperatively. Results. Although similar (approximately 50%) improvement was achieved in the severity of motor and major nonmotor symptoms in both groups, the postoperative quality of life was significantly better in the "active job" group (0.687 versus 0.587, medians, p<0.05). Majority (80%) of "active job" group members were able to preserve their job 2 years after the operation. However, only a minimal portion (5%) of the "no job" group members was able to return to the world of active employees (p<0.01). Conclusions. Although our study has several limitations, our results suggest that in patients with active job the appropriately "early" usage of DBS might help preserve working capability and gain higher improvement in quality of life.

Original languageEnglish
Article number936865
JournalParkinson's Disease
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health

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  • Cite this

    Deli, G., Balás, I., Dóczi, T., Janszky, J., Karádi, K., Aschermann, Z., Nagy, F., Makkos, A., Kovács, M., Bosnyák, E., Kovács, N., & Komoly, S. (2015). Deep brain stimulation can preserve working status in Parkinson's disease. Parkinson's Disease, 2015, [936865].