Decreased cardiovagal regulation in exfoliation syndrome

Zsuzsanna Visontai, Tamás Horváth, M. Kollai, G. Holló

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

PURPOSE: To investigate the parasympathetic cardiovascular regulation, baroreflex sensitivity (BRS), and pulse wave velocity (PWV) in exfoliation syndrome (XFS). METHODS: Heart rate variability indices [standard deviation of all RR intervals (SDNN); the mean of absolute successive differences (RMSSD); the percentage of intervals differing by >50 ms from the preceding interval (pNN50); low frequency power, and high frequency power], as well as BRS and PWV, were determined on 27 consecutive white XFS patients and 20 white control subjects under standard circumstances, with controlled breath rate of 0.25 Hz. The paired t test, the Mann-Whitney U test, and the Fisher exact test were used for comparisons. RESULTS: There was no significant difference between the XFS and control groups in sex distribution, age, heart rate, blood pressure, body mass index, systemic diseases, or medication. But in XFS patients, SDNN (mean±SD, 24±7.3 vs. 49±16.5 ms), RMSSD (17±7.3 vs. 45±29.1 ms), pNN50 (1.6%±2.5% vs. 17.7%±25.9%), high frequency (112±109 vs. 479±554 ms), and BRS (4.64±2.12 vs. 9.49±4.76 ms/mm Hg for BRS+ and 5.28±2.16 vs. 10.29±4.62 ms/mm Hg for BRS-) were all significantly lower than in the control group (P

Original languageEnglish
Pages (from-to)133-138
Number of pages6
JournalJournal of Glaucoma
Volume17
Issue number2
DOIs
Publication statusPublished - Mar 2008

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Exfoliation Syndrome
Baroreflex
Pulse Wave Analysis
Heart Rate
Control Groups
Sex Distribution
Nonparametric Statistics
Body Mass Index
Blood Pressure

Keywords

  • Baroreflex sensitivity
  • Exfoliation syndrome
  • Heart rate variability
  • Pulse wave velocity

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Decreased cardiovagal regulation in exfoliation syndrome. / Visontai, Zsuzsanna; Horváth, Tamás; Kollai, M.; Holló, G.

In: Journal of Glaucoma, Vol. 17, No. 2, 03.2008, p. 133-138.

Research output: Contribution to journalArticle

Visontai, Zsuzsanna ; Horváth, Tamás ; Kollai, M. ; Holló, G. / Decreased cardiovagal regulation in exfoliation syndrome. In: Journal of Glaucoma. 2008 ; Vol. 17, No. 2. pp. 133-138.
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