Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection

Viktor Müller, Javier Flavio Vigueras-Gómez, Sebastian Bonhoeffer

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Antiviral therapy induces a rapid drop in human immunodeficiency virus type 1 viremia, but the decline of virus levels decelerates over time. Mathematical modeling demonstrates that the source of residual virus production might be a single compartment of latently infected cells with an extended distribution of activation rates.

Original languageEnglish
Pages (from-to)8963-8965
Number of pages3
JournalJournal of Virology
Volume76
Issue number17
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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