Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety

Kitti Szőke, Attila Czompa, I. Lekli, Péter Szabados-Fürjesi, Mihály Herczeg, Magdolna Csávás, A. Borbás, P. Herczegh, A. Tósaki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Herein 1H and 13C NMR spectra of ERJ-500, a new hybrid aspirin derivative, covalently conjugated to nitrogen monoxide donor linsidomine are presented as well as NMR spectra of its synthetic intermediate compounds. HPLC-MS measurements data are also included, demonstrating the stability of the linsidomine-aspirin hybrid in oxidation reactions. This data article also concerns miscellaneous myocardial parameters of isolated rat hearts as a complementation of the tables shown in the paper entitled “A new, vasoactive hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety” Szoke et al., 2019. Column tables represent data of aorta flow, aortic pressure, derivated aortic pressure and cardiac output.

Original languageEnglish
Article number104146
JournalData in Brief
Volume25
DOIs
Publication statusPublished - Aug 1 2019

Fingerprint

Molsidomine
Aspirin
Nitric Oxide
Nuclear magnetic resonance
Rats
Derivatives
Oxidation
linsidomine

Keywords

  • ERJ-500
  • Hybrid aspirin
  • Molsidomine

ASJC Scopus subject areas

  • General

Cite this

Dataset on structure, stability and myocardial effects of a new hybrid aspirin containing nitrogen monoxide-releasing molsidomine moiety. / Szőke, Kitti; Czompa, Attila; Lekli, I.; Szabados-Fürjesi, Péter; Herczeg, Mihály; Csávás, Magdolna; Borbás, A.; Herczegh, P.; Tósaki, A.

In: Data in Brief, Vol. 25, 104146, 01.08.2019.

Research output: Contribution to journalArticle

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AU - Herczeg, Mihály

AU - Csávás, Magdolna

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