Daily setup accuracy, side-effects and quality of life during and after prone positioned prostate radiotherapy

Linda Varga, Renáta Lilla Kószo, Emese Fodor, Adrienne Cserháti, Zoltán Varga, Barbara Darázs, Z. Kahán, K. Hideghéty, Emőke Borzási, Dorottya Szabo, Kitti Müllner, Anikó Maráz

Research output: Contribution to journalArticle

Abstract

Background/Aim: Exposure of organs at risk with prostate radiotherapy (RT) is lower in the prone position. This study is a prospective evaluation of setup accuracy, side-effects, and quality of life (QOL) during and after prone positioned RT. Patients and Methods: Image-guided (IG) intensity-modulated (IM) RT was administered in prone position on belly-board to 55 high-risk prostate cancer (PC) patients. Rectum diameters were measured in two areas of the symphysis at the beginning of RT and during it. Side-effects, QOL, and prostate specific symptoms (PSS) were evaluated. Results: Setup accuracy was similar to that reported in the literature. In the upper area of symphysis rectal diameters were significantly changed during treatment, but in the prostate region, no difference was detected. No change was detected in patients’ QOL and PSS during treatment, but after RT, they improved. Conclusion: Prone positioned IG-IMRT is feasible with tolerable side-effects for high-risk PC patients. Changes in QOL and PSS are insignificant during RT, while improvement after RT suggests a rapid recovery.

Original languageEnglish
Pages (from-to)3699-3705
Number of pages7
JournalAnticancer Research
Volume38
Issue number6
DOIs
Publication statusPublished - Jun 1 2018

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Prostate
Radiotherapy
Quality of Life
Prone Position
Prostatic Neoplasms
Image-Guided Radiotherapy
Organs at Risk
Intensity-Modulated Radiotherapy
Rectum
Therapeutics

Keywords

  • Belly board (BB)
  • Daily setup accuracy
  • IMRT
  • Prone
  • Prostate cancer
  • Quality of life
  • Side-effects

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Varga, L., Kószo, R. L., Fodor, E., Cserháti, A., Varga, Z., Darázs, B., ... Maráz, A. (2018). Daily setup accuracy, side-effects and quality of life during and after prone positioned prostate radiotherapy. Anticancer Research, 38(6), 3699-3705. https://doi.org/10.21873/anticanres.12648

Daily setup accuracy, side-effects and quality of life during and after prone positioned prostate radiotherapy. / Varga, Linda; Kószo, Renáta Lilla; Fodor, Emese; Cserháti, Adrienne; Varga, Zoltán; Darázs, Barbara; Kahán, Z.; Hideghéty, K.; Borzási, Emőke; Szabo, Dorottya; Müllner, Kitti; Maráz, Anikó.

In: Anticancer Research, Vol. 38, No. 6, 01.06.2018, p. 3699-3705.

Research output: Contribution to journalArticle

Varga, L, Kószo, RL, Fodor, E, Cserháti, A, Varga, Z, Darázs, B, Kahán, Z, Hideghéty, K, Borzási, E, Szabo, D, Müllner, K & Maráz, A 2018, 'Daily setup accuracy, side-effects and quality of life during and after prone positioned prostate radiotherapy', Anticancer Research, vol. 38, no. 6, pp. 3699-3705. https://doi.org/10.21873/anticanres.12648
Varga, Linda ; Kószo, Renáta Lilla ; Fodor, Emese ; Cserháti, Adrienne ; Varga, Zoltán ; Darázs, Barbara ; Kahán, Z. ; Hideghéty, K. ; Borzási, Emőke ; Szabo, Dorottya ; Müllner, Kitti ; Maráz, Anikó. / Daily setup accuracy, side-effects and quality of life during and after prone positioned prostate radiotherapy. In: Anticancer Research. 2018 ; Vol. 38, No. 6. pp. 3699-3705.
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