Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

Filip S. Ekholm, Ágnes Berényi, Lucas Lagerquist, Tiina Saloranta, I. Zupkó, G. Schneider, J. Wölfling, Reko Leino

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed.

Original languageEnglish
Pages (from-to)295-298
Number of pages4
JournalCarbohydrate Research
Volume356
DOIs
Publication statusPublished - Jul 15 2012

Fingerprint

Glycoconjugates
Anthracyclines
Saponins
Glycosylation
Biomolecules
Doxorubicin
hellebrin

Keywords

  • Anthracyclines
  • Cytotoxic activity
  • Glycoconjugates
  • Saponins

ASJC Scopus subject areas

  • Biochemistry
  • Analytical Chemistry
  • Organic Chemistry

Cite this

Cytotoxic activity of some glycoconjugates including saponins and anthracyclines. / Ekholm, Filip S.; Berényi, Ágnes; Lagerquist, Lucas; Saloranta, Tiina; Zupkó, I.; Schneider, G.; Wölfling, J.; Leino, Reko.

In: Carbohydrate Research, Vol. 356, 15.07.2012, p. 295-298.

Research output: Contribution to journalArticle

Ekholm, Filip S. ; Berényi, Ágnes ; Lagerquist, Lucas ; Saloranta, Tiina ; Zupkó, I. ; Schneider, G. ; Wölfling, J. ; Leino, Reko. / Cytotoxic activity of some glycoconjugates including saponins and anthracyclines. In: Carbohydrate Research. 2012 ; Vol. 356. pp. 295-298.
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