Cytophotometric investigations on a chronic tubular nephropathy simulating preneoplastic condition

P. Károlyi, G. Hegedüs, Z. Szentirmay, G. Deák

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Cytophotometric investigations were performed on the atypical renal tubular epithelium of a young man who died of renal failure, possibly due to chronic lead exposure. The aim of this analysis was to determine whether nuclear atypia indicates incipient malignancy or is a type of so-called "benign atypias". DNA histogram, showing euployd polyploidy supports the latter view and the dysplastic epithelial lesion is not even considered to be a preneoplastic condition.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalInternational urology and nephrology
Issue number2
Publication statusPublished - Mar 1 1989


ASJC Scopus subject areas

  • Nephrology
  • Urology

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