Systemás lupus erythematosusban szenvedö betegek cytokin termelésének vizsgálata.

Translated title of the contribution: Cytokine production in patients with systemic lupus erythematosus

G. Müzes, R. González-Cabello, C. Van Vien, J. Fehér, P. Gergely

Research output: Contribution to journalArticle

Abstract

The production of different cytokines, namely interleukin-2, interleukin-1 and tumor necrosis factor-alpha produced by peripheral immunocompetent cells was evaluated in patients with systemic lupus erythematosus in active and inactive stage of the disease. The results obtained were compared to healthy controls. It has been found that lymphocytes from both groups of SLE patients produced similarly less interleukin-2 activity. Interleukin-1 activity of monocytes was significantly reduced only in patients with active stage of the disease, whereas tumor necrosis factor-alpha production was diminished even in cases of inactive SLE. The simultaneous detection of the above mentioned cytokines may indicate further details concerning immunoregulatory disturbances of systemic lupus erythematosus.

Original languageHungarian
Pages (from-to)1971-1974
Number of pages4
JournalOrvosi Hetilap
Volume132
Issue number36
Publication statusPublished - Sep 8 1991

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Systemic Lupus Erythematosus
Cytokines
Interleukin-1
Interleukin-2
Tumor Necrosis Factor-alpha
Monocytes
Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Müzes, G., González-Cabello, R., Van Vien, C., Fehér, J., & Gergely, P. (1991). Systemás lupus erythematosusban szenvedö betegek cytokin termelésének vizsgálata. Orvosi Hetilap, 132(36), 1971-1974.

Systemás lupus erythematosusban szenvedö betegek cytokin termelésének vizsgálata. / Müzes, G.; González-Cabello, R.; Van Vien, C.; Fehér, J.; Gergely, P.

In: Orvosi Hetilap, Vol. 132, No. 36, 08.09.1991, p. 1971-1974.

Research output: Contribution to journalArticle

Müzes, G, González-Cabello, R, Van Vien, C, Fehér, J & Gergely, P 1991, 'Systemás lupus erythematosusban szenvedö betegek cytokin termelésének vizsgálata.', Orvosi Hetilap, vol. 132, no. 36, pp. 1971-1974.
Müzes, G. ; González-Cabello, R. ; Van Vien, C. ; Fehér, J. ; Gergely, P. / Systemás lupus erythematosusban szenvedö betegek cytokin termelésének vizsgálata. In: Orvosi Hetilap. 1991 ; Vol. 132, No. 36. pp. 1971-1974.
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