Cytochemical examination of acid phosphatase and beta-glucuronidase enzymes in low-grade B cell non-Hodgkin's lymphomas.

B. Telek, K. Pecze, A. Kiss, I. Altorjay, K. Rak

Research output: Contribution to journalArticle

Abstract

The differential diagnostic significance of acid phosphatase and beta-glucuronidase were studied in 77 cases of low-grade B cell non-Hodgkin's lymphomas. In most cases the results of cytochemical enzyme studies performed on malignant cells of the bone marrow were evaluated. B cell chronic lymphocytic leukaemia, centrocytic and centroblastic/centrocytic lymphomas were characterized by a weak or a negative acid phosphatase and beta-glucuronidase activity. Stronger positivity was observed in immunocytoma and in Waldenström's macroglobulinaemia, while the highest activity was found in multiple myeloma. Hairy cell leukaemia of B cell origin showed intensive tartrate-resistant acid phosphatase activity. The cytochemical examination of these lysosomal enzymes may be useful in the diagnosis of low-grade malignant lymphomas of B cell origin by completing other methods.

Original languageEnglish
Pages (from-to)872-878
Number of pages7
JournalFolia haematologica : internationales Magazin fur klinische und morphologische Blutforschung
Volume112
Issue number6
Publication statusPublished - Dec 1 1985

ASJC Scopus subject areas

  • Hematology

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