Cyproterone acetate-promoted prevention of renal cortical necrosis following testosterone + vasopressin administration

Z. Monus, F. A. Laszlo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Bilateral focal renal cortical necrosis was observed after vasopressin administration in rats pretreated for 10 days with testosterone phenyl propionate. When the androgen-receptor blocking-agent cyproterone acetate was administered together with the testosterone, the subsequent vasopressin treatment did not cause renal cortical necrosis. The results suggest the role of the androgen receptors in the kidney in the induction of the phenomenon.

Original languageEnglish
Pages (from-to)72-75
Number of pages4
JournalBritish journal of experimental pathology
Volume60
Issue number1
Publication statusPublished - Dec 1 1979

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'Cyproterone acetate-promoted prevention of renal cortical necrosis following testosterone + vasopressin administration'. Together they form a unique fingerprint.

  • Cite this