Cyclodextrin complexes of UV filters

É Fenyvesi, K. Otta, I. Kolbe, Cs Novák, J. Szejtli

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A UVA and a UVB filter (4-tert-butyl-4′-methoxydibenzoyl methane and 3-(4-methylbenzylidene) camphor) insoluble in water have been complexed with various cyclodextrins and β-cyclodextrin derivatives. The molar ratio of the included UV filter to cyclodextrin in the solid complexes have been calculated from thermal analysis data. Among the cyclodextrins studied randomly methylated β-cyclodextrin was found to be the best solubilizer of both UV filters. The photostability of a model sulfonamide drug in aqueous solution has been improved in the presence of a UVA filter solubilised by RAMEB.

Original languageEnglish
Pages (from-to)117-123
Number of pages7
JournalJournal of Inclusion Phenomena
Volume48
Issue number3-4
DOIs
Publication statusPublished - Apr 1 2004

Keywords

  • Cyclodextrin
  • Inclusion complexation
  • Photostabilisation
  • UV filters

ASJC Scopus subject areas

  • Food Science
  • Chemistry(all)
  • Condensed Matter Physics

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