Cyclodehydrogenation of 2′‐hydroxychalcones with hypervalent iodine reagent: A new synthesis of flavones

György Litkei, Katalin Gulácsi, S. Antus, Gábor Blaskó

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A new synthesis of chrysin (1) and luteolin (4) was accomplished by the cyclodehydrogenation of the appropriately substituted 2′‐hydroxychalcones 21 and 22 in the presence of iodosobenzene diacetate/potassium hydroxide in methanol. The scope and limitation of this transformation is discussed.

Original languageEnglish
Pages (from-to)1711-1715
Number of pages5
JournalLiebigs Annalen
Volume1995
Issue number9
DOIs
Publication statusPublished - Aug 23 1995

Fingerprint

Flavones
Luteolin
potassium hydroxides
Iodine
iodine
reagents
Methanol
methyl alcohol
synthesis
iodosobenzene
chrysin
potassium hydroxide

Keywords

  • 2′‐Hydroxychalcones
  • Cyclodehydrogenation
  • Flavones
  • Iodosobenzene diacetate

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Cyclodehydrogenation of 2′‐hydroxychalcones with hypervalent iodine reagent : A new synthesis of flavones. / Litkei, György; Gulácsi, Katalin; Antus, S.; Blaskó, Gábor.

In: Liebigs Annalen, Vol. 1995, No. 9, 23.08.1995, p. 1711-1715.

Research output: Contribution to journalArticle

Litkei, György ; Gulácsi, Katalin ; Antus, S. ; Blaskó, Gábor. / Cyclodehydrogenation of 2′‐hydroxychalcones with hypervalent iodine reagent : A new synthesis of flavones. In: Liebigs Annalen. 1995 ; Vol. 1995, No. 9. pp. 1711-1715.
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