Cycloaddition Reactions of Carbohydrate Derivatives. Part III. A New Route to Swainsonine Analogs.

Pál Herczegh, Imre Kovács, László Szilágyi, Martina Zsély, Ferenc Sztaricskai, Amaya Berecibar, Alain Olesker, Gabor Lukacs

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Swainsonine analogs 10 and 12 have been synthesized from D- and L-arabinose, respectively, using cyclocondensation of azomethines with Danishefsky's diene followed by stereoselective carbonyl and double bond reduction of the resulting pyridones, chain shortening and ring closure by reductive amination.

Original languageEnglish
Pages (from-to)3133-3136
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number22
DOIs
Publication statusPublished - May 26 1992

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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