Crystallization and Resolution of cis-Permethric Acid with Carbon Dioxide Antisolvent

György Bánsághi, László Lorincz, Imre Miklós Szilágyi, J. Madarász, Edit Székely

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Crystallization and resolution of cis-permethric acid (cPA) with (1R)-1-phenylethanamine (PhEA) as a resolving agent was investigated by means of gas antisolvent (GAS) and supercritical antisolvent (SAS) methods. A significant pressure effect on both the yields and diastereomeric excesses of the crystallized cPA-PhEA salts was observed in a defined pressure range. The pressure effect was found to be related to the structure and dissociation of the salts. Both methods yielded diastereomeric salts with excellent diastereoselectivity, compared to data reported in literature, and a fibrous structure of uniform fiber diameter.

Original languageEnglish
Pages (from-to)1417-1421
Number of pages5
JournalChemical Engineering and Technology
Volume37
Issue number8
DOIs
Publication statusPublished - 2014

Fingerprint

NSC 153174
Crystallization
Carbon Dioxide
Carbon dioxide
Pressure effects
Salts
Acids
Gases
Fibers

Keywords

  • Diastereomeric salt crystallization
  • Gas antisolvent process
  • Supercritical antisolvent process
  • Supercritical carbon dioxide

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)
  • Industrial and Manufacturing Engineering

Cite this

Crystallization and Resolution of cis-Permethric Acid with Carbon Dioxide Antisolvent. / Bánsághi, György; Lorincz, László; Szilágyi, Imre Miklós; Madarász, J.; Székely, Edit.

In: Chemical Engineering and Technology, Vol. 37, No. 8, 2014, p. 1417-1421.

Research output: Contribution to journalArticle

Bánsághi, György ; Lorincz, László ; Szilágyi, Imre Miklós ; Madarász, J. ; Székely, Edit. / Crystallization and Resolution of cis-Permethric Acid with Carbon Dioxide Antisolvent. In: Chemical Engineering and Technology. 2014 ; Vol. 37, No. 8. pp. 1417-1421.
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