Crystal growth of drug materials by spherical crystallization

P. Szabó-Révész, M. Hasznos-Nezdei, B. Farkas, H. Göcző, K. Pintye-Hódi, I. Erős

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

One of the crystal growth processes is the production of crystal agglomerates by spherical crystallization. Agglomerates of drug materials were developed by means of non-typical (magnesium aspartate) and typical (acetylsalicylic acid) spherical crystallization techniques. The growth of particle size and the spherical form of the agglomerates resulted in formation of products with good bulk density, flow, compactibility and cohesivity properties. The crystal agglomerates were developed for direct capsule-filling and tablet-making.

Original languageEnglish
Pages (from-to)2240-2245
Number of pages6
JournalJournal of Crystal Growth
Volume237-239
Issue number1 4 III
DOIs
Publication statusPublished - Apr 2002

Keywords

  • A2. Growth from solutions
  • A2. Spherical agglomerates
  • A2. Spherical crystallization
  • B1. Acetylsalicylic acid
  • B1. Magnesium aspartate

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Inorganic Chemistry
  • Materials Chemistry

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