Cryopreservation of manipulated embryos: Tackling the double jeopardy

A. Dinnyes, T. L. Nedambale

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The aim of the present review is to provide information to researchers and practitioners concerning the reasons for the altered viability and the medium- and long-term consequences of cryopreservation of manipulated mammalian embryos. Embryo manipulation is defined herein as the act or process of manipulating mammalian embryos, including superovulation, AI, IVM, IVF, in vitro culture, intracytoplasmic sperm injection, embryo biopsy or splitting, somatic cell nuclear transfer cloning, the production of sexed embryos (by sperm sexing), embryo cryopreservation, embryo transfer or the creation of genetically modified (transgenic) embryos. With advances in manipulation technologies, the application of embryo manipulation will become more frequent; the proper prevention and management of the resulting alterations will be crucial in establishing an economically viable animal breeding technology.

Original languageEnglish
Pages (from-to)45-59
Number of pages15
JournalReproduction, Fertility and Development
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

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ASJC Scopus subject areas

  • Biotechnology
  • Reproductive Medicine
  • Animal Science and Zoology
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Developmental Biology

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