Covalent grafting of copper-amino acid complexes onto chloropropylated silica gel - An FT-IR study

N. I. Jakab, K. Hernádi, J. T. Kiss, I. Pálinkó

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Cu(amino acid) complexes were immobilised on silica gel by covalent anchoring. The amino acids were L-histidine and L-tyrosine and their BOC - (tert-butoxycarbonyl) or methyl ester protected derivatives. To gain control over the synthesis the appropriately protected amino acid was reacted with chloropropylated silica gel first. This modified material as is, or after deprotecting the anchored amino acids, was used in further steps of building the immobilised Cu(II) complex. The covalently grafted complexes were studied by FT-IR spectroscopy and computer modelling. Materials containing protected histidine ligands showed catalase activity (decomposition of H2O 2), those containing protected or unprotected tyrosine ligands displayed tyrosinase activity (the decomposed H2O2 oxidised the tyrosine skeleton to a quinoidal structure).

Original languageEnglish
Pages (from-to)487-494
Number of pages8
JournalJournal of Molecular Structure
Volume744-747
Issue numberSPEC. ISS.
DOIs
Publication statusPublished - Jun 3 2005

Fingerprint

Silica Gel
Silica gel
silica gel
amino acids
Amino acids
Copper
tyrosine
Tyrosine
Amino Acids
copper
histidine
Histidine
Ligands
catalase
ligands
Monophenol Monooxygenase
Gain control
musculoskeletal system
Skeleton
Catalase

Keywords

  • BOC-L-histidine
  • BOC-L-tyrosine
  • Covalent grafting
  • Cu(amino acid) complexes
  • FT-IR spectroscopy
  • HO decomposition
  • L-histidine
  • L-histidine methyl ester
  • L-tyrosine
  • L-tyrosine methyl ester
  • Molecular modelling
  • Silica gel

ASJC Scopus subject areas

  • Structural Biology
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Atomic and Molecular Physics, and Optics
  • Materials Science (miscellaneous)

Cite this

Covalent grafting of copper-amino acid complexes onto chloropropylated silica gel - An FT-IR study. / Jakab, N. I.; Hernádi, K.; Kiss, J. T.; Pálinkó, I.

In: Journal of Molecular Structure, Vol. 744-747, No. SPEC. ISS., 03.06.2005, p. 487-494.

Research output: Contribution to journalArticle

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AU - Hernádi, K.

AU - Kiss, J. T.

AU - Pálinkó, I.

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