The 15N NMR spectra of both P(2) diastereomers of the trans-fused 2-bis(2-chloroethyl)amino-3,4,4a,5,6,7,8,8a-octahydro-1,3,2λ 5-benzoxazaphosphinin-2-ones and their 3-methyl and 3-benzyl derivatives have been measured. Depending on the P(2) configuration, the coupling constants 1J(15N,31P) vary markedly. The applicability of the coupling between exocyclic nitrogen and phosphorus for determination of the heteroring conformation is discussed.
|Number of pages||3|
|Journal||Journal of the Chemical Society. Perkin Transactions 2|
|Publication status||Published - Dec 1 1997|
ASJC Scopus subject areas