Coumaryl crown ether based chemosensors: Selective detection of saxitoxin in the presence of sodium and potassium ions

Péter Kele, Jhony Orbulescu, Tiffany L. Calhoun, Robert E. Gawley, Roger M. Leblanc

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Two novel fluorescent chemosensors in which an aza-crown is linked to 4-coumaryl fluorophores by a methylene spacer have been synthesized for sensing saxitoxin. Fluorescence enhancement was observed upon binding of the dicationic toxin molecule, whereas several metal ions produced no effect.

Original languageEnglish
Pages (from-to)4413-4416
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number25
DOIs
Publication statusPublished - Jun 17 2002

Keywords

  • Coumarin
  • Fluorescence
  • Saxitoxin

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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