Az atópiás dermatitis új terapias lehetô sége A pimecrolimuskezelés hazai koltséghaté konysági elemzése

Translated title of the contribution: Cost-effectiveness of pimecrolimus cream a new treatment for atopic dermatitis in hungary

Kosa Józseť, Kalo Zoitán, Hunyadi Jánoš, Szalai Zsuzsanna, Körmendy Miklós

Research output: Contribution to journalArticle


OBJECTIVE - To assess the costs, consequences and cost-effectiveness of pimecrolimus cream 1% in the treatment of children with atopic dermatitis in Hungary. METHODS - A Markov-model for atopic dermatitis developed by the Erasmus University (Rotterdam, the Netherlands) was adopted to the Hungarian health care setting. The model is based on a double-blind, multicenter, randomized, parallel-group stud.. patients were randomised (2:1) to receive pimecrolimus treatment. (i.e. emollients, pimecrolimus medium potency topical corticosteroids) or standard of care (emollients, vehicle, medium potency topical corticosteroids). The study was conducted in children and adolescents (2 to 18 years of age). Hungarian cost vectors were calculated by linking severity of disease as defined by Investigator's Global Assessment (IGA) to average resource use. Resource use was multiplied by drug costs and unit costs as published in official databases. RESULTS - Pimecrolimus treatment has an incremental cost of HUF 143 897 over standard care. This additional cost of care resulted in an incremental 0.05 QALY gain over the 6 months period. The incremental cost effectiveness ratio was 2 863 913 HUF/QALY for the pimecrolimus therapy. CONCLUSION - Pimecrolimus is more cost-effective than many other health care interventions currently reimbursed by the Hungarian National Health Fund.

Original languageHungarian
Pages (from-to)683-689
Number of pages7
JournalLege Artis Medicinae
Issue number10
Publication statusPublished - Dec 1 2004


ASJC Scopus subject areas

  • Medicine(all)

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