A gastro-oesophagealis refluxbetegség és az obstruktív alvási apnoe kapcsolatának vizsgálata.

Translated title of the contribution: Correlations between gastroesophageal reflux disease and obstructive sleep apnea

P. Demeter, Visy Katalin Várdi, P. Magyar

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

INTRODUCTION: Several studies have reported an increased prevalence of gastroesophageal reflux disease in patients with obstructive sleep apnea. The increasingly negative intrathoracic and transdiaphragmatic pressure should facilitate of reflux-events during apnea. AIMS: The aim of the present study was to investigate whether there exists a link between endoscopic severity of reflux disease and the parameters of obstructive sleep apnea and the typical symptoms of reflux disease. METHODS: 57 patients with proven obstructive sleep apnea were divided into two groups according to the severity of the sleep apnea: "mild-moderate"--apnea-hypopnea index > or = 5-30, n = 27, "severe"--apnea-hypopnea index > 30, n = 30. All patients underwent upper panendoscopy, apnea monitoring during the night and were asked about existing and frequency of typical reflux symptoms. RESULTS: All examined patients in both groups showed significant overweight and there was a positive correlation between body mass index and the degree of sleep apnea (p = 0.0002). The occurrence of erosive reflux disease was significantly higher in "severe" group (p = 0.0001). Using a logistic regression analysis a positive correlation was found between endoscopic severity of reflux disease and apnea-hypopnea index (p = 0.016). 49.5% of all patients experienced the typical symptoms of reflux disease at least three times a week and there was not significant difference between groups. CONCLUSION: The study reveals that in patients with severe obstructive sleep apnea, erosive reflux disease is more frequent and a positive correlation can be found between severity of reflux disease and sleep apnea as well.

Original languageHungarian
Pages (from-to)1897-1901
Number of pages5
JournalOrvosi Hetilap
Volume145
Issue number37
Publication statusPublished - Sep 12 2004

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Obstructive Sleep Apnea
Gastroesophageal Reflux
Apnea
Sleep Apnea Syndromes
Body Mass Index
Logistic Models
Regression Analysis
Pressure

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A gastro-oesophagealis refluxbetegség és az obstruktív alvási apnoe kapcsolatának vizsgálata. / Demeter, P.; Várdi, Visy Katalin; Magyar, P.

In: Orvosi Hetilap, Vol. 145, No. 37, 12.09.2004, p. 1897-1901.

Research output: Contribution to journalArticle

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