Correlation of IgG Fc receptors on granulocytes with serum immune complex level in systemic lupus erythematosus

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The expression of FcγRI, FcγRII and FcγRIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated. The relationship between the receptor expression and serum immune complex (IC) concentration was analysed. The decrease in mean fluorescence intensity of both FcγRII and FcγRIII of patients' granulocytes stained by specific monoclonal antibodies (using MoAb IV.3 and 3G8) was significant. The detected decrease of FcγRII was inversely correlated with the high circulating IC level in patients' sera.

Original languageEnglish
Pages (from-to)577-580
Number of pages4
JournalScandinavian Journal of Immunology
Volume42
Issue number5
DOIs
Publication statusPublished - 1995

Fingerprint

IgG Receptors
Fc Receptors
Antigen-Antibody Complex
Granulocytes
Systemic Lupus Erythematosus
Serum
Fluorescence
Monoclonal Antibodies

ASJC Scopus subject areas

  • Immunology

Cite this

@article{ef6c7fe7a36f4b0fbda58de6cd5d3e77,
title = "Correlation of IgG Fc receptors on granulocytes with serum immune complex level in systemic lupus erythematosus",
abstract = "The expression of FcγRI, FcγRII and FcγRIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated. The relationship between the receptor expression and serum immune complex (IC) concentration was analysed. The decrease in mean fluorescence intensity of both FcγRII and FcγRIII of patients' granulocytes stained by specific monoclonal antibodies (using MoAb IV.3 and 3G8) was significant. The detected decrease of FcγRII was inversely correlated with the high circulating IC level in patients' sera.",
author = "G. Szűcs and M. Kavai and E. Kiss and I. Cs{\'i}pő and G. Szegedi",
year = "1995",
doi = "10.1111/j.1365-3083.1995.tb03699.x",
language = "English",
volume = "42",
pages = "577--580",
journal = "Scandinavian Journal of Immunology",
issn = "0300-9475",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Correlation of IgG Fc receptors on granulocytes with serum immune complex level in systemic lupus erythematosus

AU - Szűcs, G.

AU - Kavai, M.

AU - Kiss, E.

AU - Csípő, I.

AU - Szegedi, G.

PY - 1995

Y1 - 1995

N2 - The expression of FcγRI, FcγRII and FcγRIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated. The relationship between the receptor expression and serum immune complex (IC) concentration was analysed. The decrease in mean fluorescence intensity of both FcγRII and FcγRIII of patients' granulocytes stained by specific monoclonal antibodies (using MoAb IV.3 and 3G8) was significant. The detected decrease of FcγRII was inversely correlated with the high circulating IC level in patients' sera.

AB - The expression of FcγRI, FcγRII and FcγRIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated. The relationship between the receptor expression and serum immune complex (IC) concentration was analysed. The decrease in mean fluorescence intensity of both FcγRII and FcγRIII of patients' granulocytes stained by specific monoclonal antibodies (using MoAb IV.3 and 3G8) was significant. The detected decrease of FcγRII was inversely correlated with the high circulating IC level in patients' sera.

UR - http://www.scopus.com/inward/record.url?scp=0028858090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028858090&partnerID=8YFLogxK

U2 - 10.1111/j.1365-3083.1995.tb03699.x

DO - 10.1111/j.1365-3083.1995.tb03699.x

M3 - Article

C2 - 7481565

AN - SCOPUS:0028858090

VL - 42

SP - 577

EP - 580

JO - Scandinavian Journal of Immunology

JF - Scandinavian Journal of Immunology

SN - 0300-9475

IS - 5

ER -