Correlation of biochemical tumor markers with conventional pathological features in primary breast cancer

G. Péley, A. Bezzegh, I. Besznyák, Z. Doleschall, O. Csuka, I. Péter, J. Tóth, I. Számel, B. Schumann, S. Ottó

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In this prospective study the correlation of pathological with biological prognostic factors and serum tumor markers has been investigated in 574 patients with primary invasive breast cancer. The p53 protein and Bax level correlated positively with tumor size, lymph node status and histological grade. The serum levels of CEA, CA 15.3, TPA-M and TK correlated with tumor extent. There was a significant difference between pre- and postmenopausal breast cancer patients in serum levels of TPA-M and cytosol levels of Bax. Whether these correlations can help in predicting the prognosis of breast cancer by providing additional information with respect to the conventional factors, will have to be investigated by several years of careful clinical follow-up.

Original languageEnglish
Pages (from-to)49-51
Number of pages3
JournalInternational Journal of Biological Markers
Volume14
Issue number1
Publication statusPublished - Jan 1999

Fingerprint

Tumor Biomarkers
Tumors
Breast Neoplasms
bcl-2-Associated X Protein
Biological Factors
Serum
Cytosol
Neoplasms
Biomarkers
Lymph Nodes
Prospective Studies

Keywords

  • Bax
  • Breast cancer
  • p53
  • Serum markers
  • Tissue markers

ASJC Scopus subject areas

  • Immunology
  • Biochemistry

Cite this

Péley, G., Bezzegh, A., Besznyák, I., Doleschall, Z., Csuka, O., Péter, I., ... Ottó, S. (1999). Correlation of biochemical tumor markers with conventional pathological features in primary breast cancer. International Journal of Biological Markers, 14(1), 49-51.

Correlation of biochemical tumor markers with conventional pathological features in primary breast cancer. / Péley, G.; Bezzegh, A.; Besznyák, I.; Doleschall, Z.; Csuka, O.; Péter, I.; Tóth, J.; Számel, I.; Schumann, B.; Ottó, S.

In: International Journal of Biological Markers, Vol. 14, No. 1, 01.1999, p. 49-51.

Research output: Contribution to journalArticle

Péley, G, Bezzegh, A, Besznyák, I, Doleschall, Z, Csuka, O, Péter, I, Tóth, J, Számel, I, Schumann, B & Ottó, S 1999, 'Correlation of biochemical tumor markers with conventional pathological features in primary breast cancer', International Journal of Biological Markers, vol. 14, no. 1, pp. 49-51.
Péley, G. ; Bezzegh, A. ; Besznyák, I. ; Doleschall, Z. ; Csuka, O. ; Péter, I. ; Tóth, J. ; Számel, I. ; Schumann, B. ; Ottó, S. / Correlation of biochemical tumor markers with conventional pathological features in primary breast cancer. In: International Journal of Biological Markers. 1999 ; Vol. 14, No. 1. pp. 49-51.
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