Correlation between the physical characteristics of aqueous PVA solutions and the average diameter of electrospun nanofibers

Attila Vajdai, Zsombor K. Nagy, Judit Dredán, Barnabás Szabó, Romána Zelkó, György Marosi, Gabriella Ujhelyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Optimization of physical characteristics influencing the formation of electrospun poly(vinyl alcohol) (PVA) fibers designed for drug delivery system was performed. The viscosity and dynamic surface tension of solutions of PVA with different molecular weight were compared. The best circumstances for forming nanofibers, optimal for rapid drug release, were determined. The function between the studied physical features and the average nanofiber diameter was expressed mathematically in order to promote the design of nanofiber type drug delivery systems.

Original languageEnglish
Pages (from-to)1513-1517
Number of pages5
JournalLatin American Journal of Pharmacy
Volume31
Issue number10
Publication statusPublished - Dec 1 2012

Keywords

  • Average diameter of nanofibers
  • Dynamic surface tension
  • Electrospinning of pva
  • Nanofibers
  • Viscosity

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Drug Discovery

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