Correlation between severity of endoscopic findings and apnea-hypopnea index in patients with gastroesophageal reflux disease and obstructive sleep apnea

P. Demeter, Katalin Várdi Visy, P. Magyar

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Aim: To assess the relationship between severity of gastroesophageal reflux disease and apnea-hypopnea index (AHI) as an indicator of the severity of obstructive sleep apnea. Methods: Data of 57 patients with proven obstructive sleep apnea and gastroesophageal reflux disease were analyzed. Patients were divided into two groups according to severity of the sleep apnea: "mild-moderate" (A)-AHI ≥5-30, n = 27, "severe" (B)-AHI >30, n = 30. All patients underwent apnea monitoring during the night, upper panendoscopy and were asked about typical reflux symptoms. Results: All examined patients in both groups showed a significant overweight and there was a positive correlation between body mass index and the degree of sleep apnea (P = 0.0002). The occurence of erosive reflux disease was significantly higher in "severe" group (P = 0.0001). Using a logistic regression analysis a positive correlation was found between the endoscopic severity of reflux disease and the AHI (P = 0.016). Forty-nine point five percent of the patients experienced the typical symptoms of reflux disease at least three times a week and there was no significant difference between the two groups. Conclusion: A positive correlation can be found between the severity of gastroesophageal reflux disease and obstructive sleep apne.

Original languageEnglish
Pages (from-to)839-841
Number of pages3
JournalWorld Journal of Gastroenterology
Volume11
Issue number6
Publication statusPublished - Feb 14 2005

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Obstructive Sleep Apnea
Apnea
Gastroesophageal Reflux
Sleep Apnea Syndromes
Sleep
Body Mass Index
Logistic Models
Regression Analysis

Keywords

  • Correlation
  • Gastroesophageal reflux disease
  • Obstructive sleep apnea
  • Severity

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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abstract = "Aim: To assess the relationship between severity of gastroesophageal reflux disease and apnea-hypopnea index (AHI) as an indicator of the severity of obstructive sleep apnea. Methods: Data of 57 patients with proven obstructive sleep apnea and gastroesophageal reflux disease were analyzed. Patients were divided into two groups according to severity of the sleep apnea: {"}mild-moderate{"} (A)-AHI ≥5-30, n = 27, {"}severe{"} (B)-AHI >30, n = 30. All patients underwent apnea monitoring during the night, upper panendoscopy and were asked about typical reflux symptoms. Results: All examined patients in both groups showed a significant overweight and there was a positive correlation between body mass index and the degree of sleep apnea (P = 0.0002). The occurence of erosive reflux disease was significantly higher in {"}severe{"} group (P = 0.0001). Using a logistic regression analysis a positive correlation was found between the endoscopic severity of reflux disease and the AHI (P = 0.016). Forty-nine point five percent of the patients experienced the typical symptoms of reflux disease at least three times a week and there was no significant difference between the two groups. Conclusion: A positive correlation can be found between the severity of gastroesophageal reflux disease and obstructive sleep apne.",
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