Coronary revascularization in transition from on-pump to off-pump: The effect of the off-pump coronary artery bypass on medium-term outcome

J. Gál, A. Grattan, M. Kertai, A. Smith, A. D. Shaw, D. Royston, B. J. Riedel

Research output: Contribution to journalArticle

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Abstract

Aim. We previously reported that early patient outcome, chiefly ischaemic injury, was reduced in patients allocated to off pump coronary artery bypass (OPCAB) surgery. This report concerns the medium-term outcome for this cohort of patients. Methods. A prospective observational study was carried out in a single cardiothoracic specialty hospital. Forty-four patients scheduled for elective multivessel coronary artery bypass grafting (CABG) surgery using either off pump (OPCAB) (n=21) or on pump (cardiopulmonary bypass, CPB) (n=23) were included in the study. Data on the symptoms, quality of life, need for cardiovascular therapy, and occurrence of cardiovascular events or death among patients at 6- and 12-months after surgery were collected by a patient questionnaire and reviewing the medical charts. Results. Compared with patients who underwent CPB surgery, OPCAB patients required a smaller increase in cardiovascular medication (5.6% versus 47.1%; P=0.007) at the 6-month follow-up and demonstrated a trend toward improved symptoms (dyspnea at 6 months, 0, range 0-4 versus 1, range 0-4; P=0.03) and quality of life (Duke Activity Status Index at 6 months, 20.8+5.6 versus 19+6.8; P=0.13). No differences in the incidence of cardiologic intervention or mortality were observed between groups. Conclusion. The trend toward improved medium-term outcome variables among patients treated with OPCAB may have owed to the reduced cardiac ischemic injury associated with OPCAB compared with CPB.

Original languageEnglish
Pages (from-to)67-72
Number of pages6
JournalJournal of Cardiovascular Surgery
Volume48
Issue number1
Publication statusPublished - Feb 2007

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Off-Pump Coronary Artery Bypass
Cardiopulmonary Bypass
Coronary Artery Bypass
Quality of Life
Wounds and Injuries
Dyspnea
Observational Studies
Prospective Studies
Mortality
Incidence

Keywords

  • Cardiopulmonary bypass
  • Coronary artery bypass
  • Treatmen, outcome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Coronary revascularization in transition from on-pump to off-pump : The effect of the off-pump coronary artery bypass on medium-term outcome. / Gál, J.; Grattan, A.; Kertai, M.; Smith, A.; Shaw, A. D.; Royston, D.; Riedel, B. J.

In: Journal of Cardiovascular Surgery, Vol. 48, No. 1, 02.2007, p. 67-72.

Research output: Contribution to journalArticle

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abstract = "Aim. We previously reported that early patient outcome, chiefly ischaemic injury, was reduced in patients allocated to off pump coronary artery bypass (OPCAB) surgery. This report concerns the medium-term outcome for this cohort of patients. Methods. A prospective observational study was carried out in a single cardiothoracic specialty hospital. Forty-four patients scheduled for elective multivessel coronary artery bypass grafting (CABG) surgery using either off pump (OPCAB) (n=21) or on pump (cardiopulmonary bypass, CPB) (n=23) were included in the study. Data on the symptoms, quality of life, need for cardiovascular therapy, and occurrence of cardiovascular events or death among patients at 6- and 12-months after surgery were collected by a patient questionnaire and reviewing the medical charts. Results. Compared with patients who underwent CPB surgery, OPCAB patients required a smaller increase in cardiovascular medication (5.6{\%} versus 47.1{\%}; P=0.007) at the 6-month follow-up and demonstrated a trend toward improved symptoms (dyspnea at 6 months, 0, range 0-4 versus 1, range 0-4; P=0.03) and quality of life (Duke Activity Status Index at 6 months, 20.8+5.6 versus 19+6.8; P=0.13). No differences in the incidence of cardiologic intervention or mortality were observed between groups. Conclusion. The trend toward improved medium-term outcome variables among patients treated with OPCAB may have owed to the reduced cardiac ischemic injury associated with OPCAB compared with CPB.",
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