Coronary flow velocity reserve and aortic distensibility indices in hypertensive patients with hypercholesterolaemia and normal epicardial coronary arteries

Attila Nemes, T. Forster, M. Csanády

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 18 high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 ± 0.75 vs. 1.97 ± 0.60, p <0.05), increased aortic elastic modulus (in 103 mmHg) (0.56 ± 0.41 vs. 0.77 ± 0.29, p <0.05) and Young's modulus (in 10 3 mmHg) (5.42 ± 4.03 vs. 8.57 ± 4.79, p <0.05) were found in hypercholesterolaemia.

Original languageEnglish
Pages (from-to)380-387
Number of pages8
JournalClinical and Experimental Hypertension
Volume31
Issue number4
DOIs
Publication statusPublished - 2009

Fingerprint

Elastic Modulus
Hypercholesterolemia
Coronary Vessels
Cholesterol
Stress Echocardiography
Transesophageal Echocardiography
Coronary Artery Disease
Hypertension

Keywords

  • Aortic
  • Coronary flow reserve
  • Distensibility
  • Echocardiography
  • Hypercholesterolaemia
  • Hypertension
  • Stiffness

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology

Cite this

@article{05475e8b4ca74bf78abb93023ea4c766,
title = "Coronary flow velocity reserve and aortic distensibility indices in hypertensive patients with hypercholesterolaemia and normal epicardial coronary arteries",
abstract = "The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 18 high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 ± 0.75 vs. 1.97 ± 0.60, p <0.05), increased aortic elastic modulus (in 103 mmHg) (0.56 ± 0.41 vs. 0.77 ± 0.29, p <0.05) and Young's modulus (in 10 3 mmHg) (5.42 ± 4.03 vs. 8.57 ± 4.79, p <0.05) were found in hypercholesterolaemia.",
keywords = "Aortic, Coronary flow reserve, Distensibility, Echocardiography, Hypercholesterolaemia, Hypertension, Stiffness",
author = "Attila Nemes and T. Forster and M. Csan{\'a}dy",
year = "2009",
doi = "10.1080/10641960903030186",
language = "English",
volume = "31",
pages = "380--387",
journal = "Clinical and Experimental Hypertension",
issn = "1064-1963",
publisher = "Informa Healthcare",
number = "4",

}

TY - JOUR

T1 - Coronary flow velocity reserve and aortic distensibility indices in hypertensive patients with hypercholesterolaemia and normal epicardial coronary arteries

AU - Nemes, Attila

AU - Forster, T.

AU - Csanády, M.

PY - 2009

Y1 - 2009

N2 - The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 18 high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 ± 0.75 vs. 1.97 ± 0.60, p <0.05), increased aortic elastic modulus (in 103 mmHg) (0.56 ± 0.41 vs. 0.77 ± 0.29, p <0.05) and Young's modulus (in 10 3 mmHg) (5.42 ± 4.03 vs. 8.57 ± 4.79, p <0.05) were found in hypercholesterolaemia.

AB - The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 18 high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 ± 0.75 vs. 1.97 ± 0.60, p <0.05), increased aortic elastic modulus (in 103 mmHg) (0.56 ± 0.41 vs. 0.77 ± 0.29, p <0.05) and Young's modulus (in 10 3 mmHg) (5.42 ± 4.03 vs. 8.57 ± 4.79, p <0.05) were found in hypercholesterolaemia.

KW - Aortic

KW - Coronary flow reserve

KW - Distensibility

KW - Echocardiography

KW - Hypercholesterolaemia

KW - Hypertension

KW - Stiffness

UR - http://www.scopus.com/inward/record.url?scp=70849127031&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70849127031&partnerID=8YFLogxK

U2 - 10.1080/10641960903030186

DO - 10.1080/10641960903030186

M3 - Article

C2 - 19811366

AN - SCOPUS:70849127031

VL - 31

SP - 380

EP - 387

JO - Clinical and Experimental Hypertension

JF - Clinical and Experimental Hypertension

SN - 1064-1963

IS - 4

ER -