Coronary flow velocity reserve and aortic distensibility indices in hypertensive patients with hypercholesterolaemia and normal epicardial coronary arteries

Attila Nemes, Tams Forster, Mikls Csandy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The aim of the present study was to assess the relationship between coronary flow velocity reserve (CFR), aortic distensibility indices, and levels of plasma total cholesterol (TC) in arterial hypertension. We studied 39 consecutive hypertensive patients free of coronary artery disease. Eighteen of them had normal TC and 21 had 18 high TC. Coronary flow velocity reserve and aortic elastic moduli were measured during stress transoesophageal echocardiography. Reduced CFR (2.41 ± 0.75 vs. 1.97 ± 0.60, p < 0.05), increased aortic elastic modulus (in 103 mmHg) (0.56 ± 0.41 vs. 0.77 ± 0.29, p < 0.05) and Young's modulus (in 10 3 mmHg) (5.42 ± 4.03 vs. 8.57 ± 4.79, p < 0.05) were found in hypercholesterolaemia.

Original languageEnglish
Pages (from-to)380-387
Number of pages8
JournalClinical and Experimental Hypertension
Volume31
Issue number4
DOIs
Publication statusPublished - Dec 4 2009

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Keywords

  • Aortic
  • Coronary flow reserve
  • Distensibility
  • Echocardiography
  • Hypercholesterolaemia
  • Hypertension
  • Stiffness

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology

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