Copper(II) chloride as an efficient reagent for the dehydrogenation of pyridazinone derivatives

F. Csende, Z. Szabo, G. Bernath, G. Stajer

Research output: Contribution to journalArticle

18 Citations (Scopus)


A new procedure is described for the preparation of pyridazinones from 4,5-dihydropyridazinones under mild conditions with CuCl2 in MeCN via halogenation and spontaneous HCl elimination. For the trans-hexahydrophthalazin-8(1H)-one 1B*, the HCl elimination is five times faster than for the corresponding cis isomer 1B.

Original languageEnglish
Pages (from-to)1240-1242
Number of pages3
Issue number10
Publication statusPublished - Jan 1 1995


ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this