Copper on iron: Catalyst and scavenger for azide-alkyne cycloaddition

Szabolcs Kovács, Katalin Zih-Perényi, Ádám Révész, Zoltán Novák

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Dipolar cycloaddition of terminal alkynes and azides catalyzed by the Cu/Fe bimetallic system is reported. In the presence of a readily accessible nanosized copper source, the cycloaddition reaction can be easily achieved at ambient temperature with high efficiency. The product obtained from the reaction catalyzed by Cu/Fe contains significantly lower copper contaminants compared to various active homogeneous copper complexes. Iron not only behaves as support for copper, but acts as a redox scavenger, and reduces the copper contamination of the organic product.

Original languageEnglish
Article numberSS-2012-E0719-FA
Pages (from-to)3722-3730
Number of pages9
JournalSynthesis (Germany)
Volume44
Issue number24
DOIs
Publication statusPublished - Nov 21 2012

Keywords

  • alkynes
  • azides
  • copper
  • iron
  • supported catalysis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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