Coordination chemical studies of polypeptides. I. polarographic investigation of the zinc complex of synthetic αh-corticotropine [1-32]

K. Burger, G. Farsang, L. Ladányi, B. Noszál, M. Pékli, G. Takácsi Nagy

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Through the polarographic study of the interaction between zinc ions and ACTH it was established that there are two different zinc complexes in solutions at pH between 6 and 8 depending on the Zn : ACTH ratio. On the basis of the data obtained their likely composition could be also given. The formation of the zinc complexes of ACTH results in the apperance of the catalytic hydrogen discharge at lower negative potentials. This effect can be attributed to the coordination of zinc ions to the nitrogens of the heterocycle of hystidine in ACTH.

Original languageEnglish
Pages (from-to)329-338
Number of pages10
JournalBioelectrochemistry and Bioenergetics
Volume2
Issue number4
DOIs
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Biophysics
  • Physical and Theoretical Chemistry
  • Electrochemistry

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