Conversion of 6α-phenyl-7,7-dichloro-2,3-(2',3'-dimethoxy-benzo)-1-thiaoctem in the presence of base1

L. Fodor, János Szabó, G. Bernáth, P. Sohár, G. Argay, A. Kálmán, József Tamás

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Basic treatment in methanol of linearly condensed 1,3-benzothiazinedichloro-β-lactam 1 led to a 1,4-benzothiazepine 2, a tetrasubstituted isoquinoline 3, and a thiazole disulfide derivative 4 via a new ring transformation. The structure of the thiazole disulfide 4 was determined by X-ray diffraction.

Original languageEnglish
Pages (from-to)7181-7184
Number of pages4
JournalTetrahedron
Volume44
Issue number23
DOIs
Publication statusPublished - 1988

Fingerprint

Thiazoles
Disulfides
Lactams
X-Ray Diffraction
Methanol
Derivatives
X ray diffraction
isoquinoline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Conversion of 6α-phenyl-7,7-dichloro-2,3-(2',3'-dimethoxy-benzo)-1-thiaoctem in the presence of base1. / Fodor, L.; Szabó, János; Bernáth, G.; Sohár, P.; Argay, G.; Kálmán, A.; Tamás, József.

In: Tetrahedron, Vol. 44, No. 23, 1988, p. 7181-7184.

Research output: Contribution to journalArticle

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AU - Fodor, L.

AU - Szabó, János

AU - Bernáth, G.

AU - Sohár, P.

AU - Argay, G.

AU - Kálmán, A.

AU - Tamás, József

PY - 1988

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AB - Basic treatment in methanol of linearly condensed 1,3-benzothiazinedichloro-β-lactam 1 led to a 1,4-benzothiazepine 2, a tetrasubstituted isoquinoline 3, and a thiazole disulfide derivative 4 via a new ring transformation. The structure of the thiazole disulfide 4 was determined by X-ray diffraction.

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