Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale

Gérald Devuyst, Bartłomiej Piechowski-Jóźwiak, Theodoros Karapanayiotides, Jean William Fitting, V. Kemény, Lorenz Hirt, Luis A. Urbano, Pierre Arnold, Guy Van Melle, Paul Andre Despland, Julien Bogousslavsky

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background and Purpose-A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage of microbubbles, on which depends the shunt classification by c-TCD, and correlated it with the right-to-left shunt evaluation by ABG measurements in stroke patients with patent foramen ovale (PFO). Methods-We evaluated 40 stroke patients with transesophageal echocardiography-documented PFO. The microbubbles were recorded with TCD at rest and after 4 different VM conditions with controlled duration and target strain pressures (duration in seconds and pressure in cm H2O, respectively): V5-20, V 10-20, V5-40, and V 10-40. The ABG analysis was performed after pure oxygen breathing in 34 patients, and the shunt was calculated as percentage of cardiac output. Results-Among all VM conditions, V5-40 and V 10-40 yielded the greatest median number of microbubbles (84 and 95, respectively; P

Original languageEnglish
Pages (from-to)859-863
Number of pages5
JournalStroke
Volume35
Issue number4
DOIs
Publication statusPublished - Apr 2004

Fingerprint

Valsalva Maneuver
Patent Foramen Ovale
Blood Gas Analysis
Microbubbles
Doppler Transcranial Ultrasonography
Pressure
Gases
Stroke
Transesophageal Echocardiography
Cardiac Output
Respiration
Oxygen

Keywords

  • Foramen ovale, patent
  • Oxygen
  • Ultrasonography, Doppler, transcranial
  • Valsalva maneuver

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Devuyst, G., Piechowski-Jóźwiak, B., Karapanayiotides, T., Fitting, J. W., Kemény, V., Hirt, L., ... Bogousslavsky, J. (2004). Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale. Stroke, 35(4), 859-863. https://doi.org/10.1161/01.STR.0000119384.28376.EB

Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale. / Devuyst, Gérald; Piechowski-Jóźwiak, Bartłomiej; Karapanayiotides, Theodoros; Fitting, Jean William; Kemény, V.; Hirt, Lorenz; Urbano, Luis A.; Arnold, Pierre; Van Melle, Guy; Despland, Paul Andre; Bogousslavsky, Julien.

In: Stroke, Vol. 35, No. 4, 04.2004, p. 859-863.

Research output: Contribution to journalArticle

Devuyst, G, Piechowski-Jóźwiak, B, Karapanayiotides, T, Fitting, JW, Kemény, V, Hirt, L, Urbano, LA, Arnold, P, Van Melle, G, Despland, PA & Bogousslavsky, J 2004, 'Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale', Stroke, vol. 35, no. 4, pp. 859-863. https://doi.org/10.1161/01.STR.0000119384.28376.EB
Devuyst, Gérald ; Piechowski-Jóźwiak, Bartłomiej ; Karapanayiotides, Theodoros ; Fitting, Jean William ; Kemény, V. ; Hirt, Lorenz ; Urbano, Luis A. ; Arnold, Pierre ; Van Melle, Guy ; Despland, Paul Andre ; Bogousslavsky, Julien. / Controlled Contrast Transcranial Doppler and Arterial Blood Gas Analysis to Quantify Shunt Through Patent Foramen Ovale. In: Stroke. 2004 ; Vol. 35, No. 4. pp. 859-863.
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AU - Karapanayiotides, Theodoros

AU - Fitting, Jean William

AU - Kemény, V.

AU - Hirt, Lorenz

AU - Urbano, Luis A.

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