Conformations of proline-containing cyclic peptides. II. Asymmetric solution conformations of cyclo-(L-Pro2-Gly)2 and its alkaline-earth metal complexes as studied by NMR spectroscopy

L. Radics, M. Hollósi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

By 1H and 13C NMR methods, the title peptide, either free or complexed with metal ions, is shown to preferentially assume asymmetric solution conformations. Spectral data strongly suggest the occurrence of an unusual β-turn with two Pro residues in consecutive corner positions.

Original languageEnglish
Pages (from-to)4531-4534
Number of pages4
JournalTetrahedron Letters
Volume21
Issue number47
DOIs
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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