Conformational analysis of s-triazolobenzothiazine derivatives prepared by intermolecular 1,3-dipolar cycloaddition of nitrilimines to 4-aryl-2H-1,3-benzothiazines

János Szabó, L. Fodor, Ernest Bani-Akoto, Gizella S. Talpas, G. Bernáth, P. Sohár

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A series of new 1,3,10b-trisubstituted-8,9-dimethoxy-1,10b-dihydro-5H-1,2,4-triazolo[4,3-c] = [1,3]benzothiazines (2a-i) have been synthesized by thermal [3+2]-cycloaddition of nitrilimines to 4-aryl-6,7-dimethoxy-2H-1,3-benzothiazines (1a-d). Conformational analysis of the s-triazolobenzothiazine derivatives 2a-i was performed by NMR spectroscopy.

Original languageEnglish
Pages (from-to)4957-4962
Number of pages6
JournalTetrahedron
Volume48
Issue number23
DOIs
Publication statusPublished - Jun 5 1992

Fingerprint

Cycloaddition
Cycloaddition Reaction
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Hot Temperature
Derivatives

Keywords

  • 1,3,10b-Trisubstituted-8,9-dimethoxy-1,10b-dihydro-5H-1,2,4-triazolo[4,3-c][1,3]benzothiazines
  • conformational analysis
  • cycloaddition of nitrilimines
  • reaction of 4-aryl-2H-1,3-benzothiazines

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Conformational analysis of s-triazolobenzothiazine derivatives prepared by intermolecular 1,3-dipolar cycloaddition of nitrilimines to 4-aryl-2H-1,3-benzothiazines. / Szabó, János; Fodor, L.; Bani-Akoto, Ernest; Talpas, Gizella S.; Bernáth, G.; Sohár, P.

In: Tetrahedron, Vol. 48, No. 23, 05.06.1992, p. 4957-4962.

Research output: Contribution to journalArticle

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AU - Fodor, L.

AU - Bani-Akoto, Ernest

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AU - Bernáth, G.

AU - Sohár, P.

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