Conformational analyses of two pyridazino[4,5-b][1,5]oxazepines and a pyridazino[4,5-b][1,5]thiazepine+

Péter Mátyus, András P. Borosy, Miklós Morvai, Sándor Boros

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Conformational analyses of N-acylated bicyclic pyridazine derivatives 1a, 1b and 2 were carried out by semiempirical AM1 calculations and temperature dependent 1H-NMR measurements. Energy barriers of rotation around the amide bonds in these compounds are in the same ranges, and absolute differences between calculated and measured values are acceptable. Some ring conformations obtained by calculations are also shown.

Original languageEnglish
Pages (from-to)591-600
Number of pages10
JournalACH - Models in Chemistry
Volume135
Issue number4
Publication statusPublished - Dec 1 1998

ASJC Scopus subject areas

  • Chemistry(all)

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