Cones in the retina of the Mongolian gerbil, Meriones unguiculatus: an immunocytochemical and electrophysiological study

V. I. Govardovskii, P. Röhlich, A. Szél, T. V. Khokhlova

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50 Citations (Scopus)

Abstract

Immunocytochemistry revealed in the retina of the Mongolian gerbil three immunologically distinct photoreceptor cell types. Rods comprising about 87% of the total receptor population were selectively recognized by an antirhodopsin serum (AO). The most abundant cone type (11-13% of photo receptors) was labeled by the monoclonal antibody COS-1, specific in mammals to the middle-to-longwave sensitive cone visual pigments. A minor cone population (2.5-5% of the cones) reacted with the monoclonal antibody OS-2, shown earlier to bind to the blue cones in mammalian species. Color substitution experiments revealed on the ERG level a color discrimination capability which must be attributed to the cooperative activity of green-sensitive (COS-1 positive) and blue-sensitive (OS-2 positive) cones. We conclude that the Mongolian gerbil has a well developed cone system, and that it may possess dichromatic green-blue color vision.

Original languageEnglish
Pages (from-to)19-27
Number of pages9
JournalVision Research
Volume32
Issue number1
DOIs
Publication statusPublished - Jan 1992

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Keywords

  • Color vision
  • Cones
  • Electrophysiology
  • Immunocytochemistry
  • Meriones unguiculatus
  • Rodents

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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