Concise Review: Saliva and Growth Factors: The Fountain of Youth Resides in Us All

T. Zelles, K. R. Purushotham, S. P. Macauley, G. E. Oxford, M. G. Humphreys-Beher

Research output: Contribution to journalReview article

107 Citations (Scopus)

Abstract

The predominant focus of research dealing with saliva revolves around the role in the maintenance of oral health through a number of physiological and biological properties of constituent proteins. An ever-expanding literature exists indicating that the salivary glands additionally synthesize, and secrete into saliva, a wide range of growth factors. Animal studies with epidermal growth factor have provided evidence for a role in both oral and systemic health, through the promotion of wound healing rates. Thus, the ability to manipulate their rates of synthesis and absorption from saliva holds the potential to enhance tissue regeneration and homeostasis.

Original languageEnglish
Pages (from-to)1826-1832
Number of pages7
JournalJournal of dental research
Volume74
Issue number12
DOIs
Publication statusPublished - Dec 1995

Keywords

  • epidermal growth factor
  • saliva
  • salivary glands
  • wound healing

ASJC Scopus subject areas

  • Dentistry(all)

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    Zelles, T., Purushotham, K. R., Macauley, S. P., Oxford, G. E., & Humphreys-Beher, M. G. (1995). Concise Review: Saliva and Growth Factors: The Fountain of Youth Resides in Us All. Journal of dental research, 74(12), 1826-1832. https://doi.org/10.1177/00220345950740120301