Computer simulation of the selectivity of a model calcium channel

Dezsö Boda, Douglas Henderson

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Biological channels are protein molecules that contain a hole and that allow selected ions to pass through a membrane. They provide the mechanism for the control of many physiological functions. For example, a calcium channel selects calcium ions and controls the beating of a heart. We report our Monte Carlo results on model calcium channels. Because of the presence of negatively charged glutamate side chains in the channel, the channel selects calcium ions over sodium ions because of the ability of the divalent calcium ions to deliver twice the charge while occupying the same volume as the monovalent ions in the narrow channel.

Original languageEnglish
Pages (from-to)9485-9488
Number of pages4
JournalJournal of Physics Condensed Matter
Volume14
Issue number41
DOIs
Publication statusPublished - Oct 21 2002

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics

Fingerprint Dive into the research topics of 'Computer simulation of the selectivity of a model calcium channel'. Together they form a unique fingerprint.

  • Cite this