UBER DIE INHALTSSTOFFE DES GRUNEN KNOLLENBLATTERPILZES, LXI. δ-AMINOPHALLOIN, EIN 7-ANALOGES DES PHALLOIDINS, UND BIOCHEMISCH NUTZLICHE, AUCH FLUORESZIERENDE DERIVATE

Translated title of the contribution: Components of the green deathcap mushroom (Amanita phalloides), LXI.- δ-Aminophalloin, a 7-analogue of phalloidin, and some biochemically useful, including fluorescent derivatives

T. Wieland, M. Hollósi, M. Nassal

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Citations (Scopus)

Abstract

The tosyloxy group of O(δ7)-tosylphalloidin (1b) obtained by tosylation of the primary alcohol function of the γ,δ-dihydroxyleucine side chain (amino acid no. 7) of phalloidin (1a) is replaced by ammonia, aniline, p-hexyloxyaniline, or 4'-aminofluorescein. From δ-aminophalloin (1c) 12 new derivatives [1h-q and the bis(phallotoxins) 2a,b] are prepared. The fluorescent phalloidins 1p,q are valuable stains for visualization of F-actin. Toxicities and R(F) values of the phallotoxin derivatives are indicated.

Original languageGerman
Title of host publicationLIEBIGS ANN. CHEM.
Pages1533-1540
Number of pages8
VolumeNO. 9
Publication statusPublished - 1983

Fingerprint

Amanita
Phalloidine
Agaricales
Ammonia
Actins
Coloring Agents
Alcohols
Amino Acids
phallotoxin
4-aminofluorescein
aniline

ASJC Scopus subject areas

  • Medicine(all)

Cite this

UBER DIE INHALTSSTOFFE DES GRUNEN KNOLLENBLATTERPILZES, LXI. δ-AMINOPHALLOIN, EIN 7-ANALOGES DES PHALLOIDINS, UND BIOCHEMISCH NUTZLICHE, AUCH FLUORESZIERENDE DERIVATE. / Wieland, T.; Hollósi, M.; Nassal, M.

LIEBIGS ANN. CHEM.. Vol. NO. 9 1983. p. 1533-1540.

Research output: Chapter in Book/Report/Conference proceedingChapter

@inbook{f889dcc90a4c49bbb9e8b008030929b1,
title = "UBER DIE INHALTSSTOFFE DES GRUNEN KNOLLENBLATTERPILZES, LXI. δ-AMINOPHALLOIN, EIN 7-ANALOGES DES PHALLOIDINS, UND BIOCHEMISCH NUTZLICHE, AUCH FLUORESZIERENDE DERIVATE",
abstract = "The tosyloxy group of O(δ7)-tosylphalloidin (1b) obtained by tosylation of the primary alcohol function of the γ,δ-dihydroxyleucine side chain (amino acid no. 7) of phalloidin (1a) is replaced by ammonia, aniline, p-hexyloxyaniline, or 4'-aminofluorescein. From δ-aminophalloin (1c) 12 new derivatives [1h-q and the bis(phallotoxins) 2a,b] are prepared. The fluorescent phalloidins 1p,q are valuable stains for visualization of F-actin. Toxicities and R(F) values of the phallotoxin derivatives are indicated.",
author = "T. Wieland and M. Holl{\'o}si and M. Nassal",
year = "1983",
language = "German",
volume = "NO. 9",
pages = "1533--1540",
booktitle = "LIEBIGS ANN. CHEM.",

}

TY - CHAP

T1 - UBER DIE INHALTSSTOFFE DES GRUNEN KNOLLENBLATTERPILZES, LXI. δ-AMINOPHALLOIN, EIN 7-ANALOGES DES PHALLOIDINS, UND BIOCHEMISCH NUTZLICHE, AUCH FLUORESZIERENDE DERIVATE

AU - Wieland, T.

AU - Hollósi, M.

AU - Nassal, M.

PY - 1983

Y1 - 1983

N2 - The tosyloxy group of O(δ7)-tosylphalloidin (1b) obtained by tosylation of the primary alcohol function of the γ,δ-dihydroxyleucine side chain (amino acid no. 7) of phalloidin (1a) is replaced by ammonia, aniline, p-hexyloxyaniline, or 4'-aminofluorescein. From δ-aminophalloin (1c) 12 new derivatives [1h-q and the bis(phallotoxins) 2a,b] are prepared. The fluorescent phalloidins 1p,q are valuable stains for visualization of F-actin. Toxicities and R(F) values of the phallotoxin derivatives are indicated.

AB - The tosyloxy group of O(δ7)-tosylphalloidin (1b) obtained by tosylation of the primary alcohol function of the γ,δ-dihydroxyleucine side chain (amino acid no. 7) of phalloidin (1a) is replaced by ammonia, aniline, p-hexyloxyaniline, or 4'-aminofluorescein. From δ-aminophalloin (1c) 12 new derivatives [1h-q and the bis(phallotoxins) 2a,b] are prepared. The fluorescent phalloidins 1p,q are valuable stains for visualization of F-actin. Toxicities and R(F) values of the phallotoxin derivatives are indicated.

UR - http://www.scopus.com/inward/record.url?scp=0021041671&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021041671&partnerID=8YFLogxK

M3 - Chapter

AN - SCOPUS:0021041671

VL - NO. 9

SP - 1533

EP - 1540

BT - LIEBIGS ANN. CHEM.

ER -