Complexation of nitrostyrenes with soluble β-cyclodextrin polymer studied by reversed-phase thin-layer chromatography

T. Cserháti, Barna Bordás, Attila Kis-Tamás, Gyula Mikite, József Szejtli, Éva Fenyvesi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Cyclodextrin complexation decreases the apparent lipophilicity of hydrophobic guest molecules. A higher complex stability results in a larger decrease of lipophilicity as determined by reversed-phase thin-layer chromatography. The method was applied to study the complex formation of 33 nitrostyrene derivatives with a water soluble cross linked β-cyclodextrin polymer (weight average molecular weight: 4300). The substituents in the para position of the benzene ring had a higher impact on the complex stability than those in the meta and ortho positions. The substituents on the alkyl side chain influenced the complex stability to the same extent as those on the benzen ring.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
JournalJournal of Inclusion Phenomena
Volume4
Issue number1
DOIs
Publication statusPublished - Mar 1986

Fingerprint

thin layer chromatography
Thin layer chromatography
cyclodextrins
Cyclodextrins
Reverse-Phase Chromatography
Thin Layer Chromatography
Benzene
hydrophobicity
Complexation
polymers
Molecular Weight
Weights and Measures
Water
benzene
chemical derivatives
rings
molecular weight
Molecular weight
Derivatives
Molecules

Keywords

  • complex stability
  • Nitrostyrenes
  • soluble cyclodextrin polymer
  • thin-layer chromatography

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Chemistry(all)

Cite this

Complexation of nitrostyrenes with soluble β-cyclodextrin polymer studied by reversed-phase thin-layer chromatography. / Cserháti, T.; Bordás, Barna; Kis-Tamás, Attila; Mikite, Gyula; Szejtli, József; Fenyvesi, Éva.

In: Journal of Inclusion Phenomena, Vol. 4, No. 1, 03.1986, p. 55-59.

Research output: Contribution to journalArticle

Cserháti, T. ; Bordás, Barna ; Kis-Tamás, Attila ; Mikite, Gyula ; Szejtli, József ; Fenyvesi, Éva. / Complexation of nitrostyrenes with soluble β-cyclodextrin polymer studied by reversed-phase thin-layer chromatography. In: Journal of Inclusion Phenomena. 1986 ; Vol. 4, No. 1. pp. 55-59.
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