COMPLEX-FORMING ELUENT ADDITIVES IN REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY OF METHYLATED beta -CYCLODEXTRINS.

T. Cserháti, L. Szente, J. Szejtli

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

To study the effect of guest molecules on the lipophilicity of the hosts ( beta -cyclodextrin derivatives), the authors applied a reverted version of the principle: the guest molecule was dissolved in the eluent. It is shown that the effect of cyclohexanes is generally greater than that of cyclopentanes, suggesting that the cyclohexane ring fits better into the cavity of DIMEB and TRIMEB, resulting in a higher complex stability. Since the hydrophilic part ( minus NH//2, minus OH, and equals O) of complexed cycloalkanes protrudes from the BCD cavity, the formation of hydrogen bonds of different strength with the nonmethylated hydroxyl groups is conceivable.

Original languageEnglish
Pages (from-to)635-636
Number of pages2
JournalHRC & CC. Journal of high resolution chromatography & chromatography communications
Volume7
Issue number11
Publication statusPublished - Nov 1984

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beta-Cyclodextrins
Thin layer chromatography
Cyclohexane
Cyclohexanes
Cycloparaffins
Cyclopentanes
Molecules
Cyclodextrins
Hydroxyl Radical
Hydrogen bonds
Derivatives
betadex

ASJC Scopus subject areas

  • Engineering(all)

Cite this

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abstract = "To study the effect of guest molecules on the lipophilicity of the hosts ( beta -cyclodextrin derivatives), the authors applied a reverted version of the principle: the guest molecule was dissolved in the eluent. It is shown that the effect of cyclohexanes is generally greater than that of cyclopentanes, suggesting that the cyclohexane ring fits better into the cavity of DIMEB and TRIMEB, resulting in a higher complex stability. Since the hydrophilic part ( minus NH//2, minus OH, and equals O) of complexed cycloalkanes protrudes from the BCD cavity, the formation of hydrogen bonds of different strength with the nonmethylated hydroxyl groups is conceivable.",
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T1 - COMPLEX-FORMING ELUENT ADDITIVES IN REVERSED-PHASE THIN-LAYER CHROMATOGRAPHY OF METHYLATED beta -CYCLODEXTRINS.

AU - Cserháti, T.

AU - Szente, L.

AU - Szejtli, J.

PY - 1984/11

Y1 - 1984/11

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AB - To study the effect of guest molecules on the lipophilicity of the hosts ( beta -cyclodextrin derivatives), the authors applied a reverted version of the principle: the guest molecule was dissolved in the eluent. It is shown that the effect of cyclohexanes is generally greater than that of cyclopentanes, suggesting that the cyclohexane ring fits better into the cavity of DIMEB and TRIMEB, resulting in a higher complex stability. Since the hydrophilic part ( minus NH//2, minus OH, and equals O) of complexed cycloalkanes protrudes from the BCD cavity, the formation of hydrogen bonds of different strength with the nonmethylated hydroxyl groups is conceivable.

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