Complex-formation and redox reactions of bilirubin and biliverdin with zinc(II), cadmium(II) and copper(II) ions

I. Sóvágó, Béla Harman, Irén Kolozsvári, Ferenc Matyuska

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Transition metal complexes of bilirubin and biliverdin were studied spectrophotometrically, in DMSO and in a boric acid-NaOH buffer mixture at pH 10.5. In the zinc(II) and cadmium(II)- bilirubin systems, 2:1 complexes are formed. Both in aqueous and in DMSO medium, the copper(II) ion oxidizes bilirubin to biliverdin. With all three metal ions, biliverdin forms 1:1 complexes, the stabilities of which are higher than those of the corresponding bilirubin complexes. Accordingly, these metal ions accelerate the oxidative transformations of bilirubin.

Original languageEnglish
Pages (from-to)181-186
Number of pages6
JournalInorganica Chimica Acta
Volume106
Issue number4
DOIs
Publication statusPublished - 1985

Fingerprint

Biliverdine
Redox reactions
Cadmium
Bilirubin
cadmium
Oxidation-Reduction
Metal ions
Zinc
Copper
metal ions
zinc
Ions
copper
boric acids
Boric acid
Metal complexes
Transition metals
ions
Dimethyl Sulfoxide
buffers

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

Complex-formation and redox reactions of bilirubin and biliverdin with zinc(II), cadmium(II) and copper(II) ions. / Sóvágó, I.; Harman, Béla; Kolozsvári, Irén; Matyuska, Ferenc.

In: Inorganica Chimica Acta, Vol. 106, No. 4, 1985, p. 181-186.

Research output: Contribution to journalArticle

Sóvágó, I. ; Harman, Béla ; Kolozsvári, Irén ; Matyuska, Ferenc. / Complex-formation and redox reactions of bilirubin and biliverdin with zinc(II), cadmium(II) and copper(II) ions. In: Inorganica Chimica Acta. 1985 ; Vol. 106, No. 4. pp. 181-186.
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