Complete genome sequence of C130_2, a novel myovirus infecting pathogenic Escherichia coli and Shigella strains

Domonkos Sváb, Linda Falgenhauer, Manfred Rohde, Trinad Chakraborty, I. Tóth

Research output: Contribution to journalArticle

Abstract

The genome sequence of a novel virulent bacteriophage, named “ C130_2”, that is morphologically a member of the family Myoviridae is reported. The 41,775-base-pair double-stranded DNA genome of C130_2 contains 59 ORFs but exhibits overall low sequence similarity to bacteriophage genomes for which sequences are publicly available. Phylogenetic analysis indicated that C130_2 represents a new phage type. C130_2 could be propagated well on enterohemorrhagic Escherichia coli (EHEC) O157:H7 and other pathogenic E. coli strains, as well as on strains of various Shigella species.

Original languageEnglish
JournalArchives of Virology
DOIs
Publication statusAccepted/In press - Jan 1 2018

Fingerprint

Shigella
Bacteriophages
Genome
Escherichia coli
Myoviridae
Enterohemorrhagic Escherichia coli
Escherichia coli O157
Base Pairing
Open Reading Frames
DNA

ASJC Scopus subject areas

  • Virology

Cite this

Complete genome sequence of C130_2, a novel myovirus infecting pathogenic Escherichia coli and Shigella strains. / Sváb, Domonkos; Falgenhauer, Linda; Rohde, Manfred; Chakraborty, Trinad; Tóth, I.

In: Archives of Virology, 01.01.2018.

Research output: Contribution to journalArticle

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