Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control

Mikhail Baloban, Marleen Vanstraelen, Sylvie Tarayre, Christophe Reuzeau, Antonietta Cultrone, Peter Mergaert, É. Kondorosi

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The dimension of organs depends on the number and the size of their component cells. Formation of polyploid cells by endoreduplication cycles is predominantly associated with increases in the cell size and implicated in organ growth. In plants, the CCS52A proteins play a major role in the switch from mitotic to endoreduplication cycles controlling thus the number of mitotic cells and the endoreduplication events in the differentiating cells. Arabidopsis has two CCS52A isoforms; AtCCS52A1 and AtCCS52A2. Here we focused on their roles in endoreduplication and cell size control during plant development. We demonstrate their complementary and dose-dependent actions that are dependent on their expression patterns. Moreover, the impact of CCS52A overexpression on organ size in transgenic plants was dependent on the expression level; while enhanced expression of the CCS52A genes positively correlated with the ploidy levels, organ sizes were negatively affected by strong overexpression whereas milder overexpression resulted in a significant increase in the organ sizes. Taken together, these finding support both complementary and dose-dependent actions for the Arabidopsis CCS52A isoforms in plant development and demonstrate that elevated ectopic CCS52A expression positively correlates with organ size, opening a route to higher biomass production.

Original languageEnglish
Pages (from-to)1049-1059
Number of pages11
JournalNew Phytologist
Volume198
Issue number4
DOIs
Publication statusPublished - Jun 2013

Fingerprint

Endoreduplication
endopolyploidy
Organ Size
Protein Isoforms
Plant Development
dosage
Cell Size
Arabidopsis
cells
Plant Proteins
Polyploidy
plant development
Ploidies
Genetically Modified Plants
Cellular Structures
Biomass
Cell Cycle
Cell Count
plant proteins
ploidy

Keywords

  • Anaphase-promoting complex (APC)
  • CDH1
  • Cell size
  • Endoreduplication
  • Organ size

ASJC Scopus subject areas

  • Plant Science
  • Physiology

Cite this

Baloban, M., Vanstraelen, M., Tarayre, S., Reuzeau, C., Cultrone, A., Mergaert, P., & Kondorosi, É. (2013). Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control. New Phytologist, 198(4), 1049-1059. https://doi.org/10.1111/nph.12216

Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control. / Baloban, Mikhail; Vanstraelen, Marleen; Tarayre, Sylvie; Reuzeau, Christophe; Cultrone, Antonietta; Mergaert, Peter; Kondorosi, É.

In: New Phytologist, Vol. 198, No. 4, 06.2013, p. 1049-1059.

Research output: Contribution to journalArticle

Baloban, M, Vanstraelen, M, Tarayre, S, Reuzeau, C, Cultrone, A, Mergaert, P & Kondorosi, É 2013, 'Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control', New Phytologist, vol. 198, no. 4, pp. 1049-1059. https://doi.org/10.1111/nph.12216
Baloban M, Vanstraelen M, Tarayre S, Reuzeau C, Cultrone A, Mergaert P et al. Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control. New Phytologist. 2013 Jun;198(4):1049-1059. https://doi.org/10.1111/nph.12216
Baloban, Mikhail ; Vanstraelen, Marleen ; Tarayre, Sylvie ; Reuzeau, Christophe ; Cultrone, Antonietta ; Mergaert, Peter ; Kondorosi, É. / Complementary and dose-dependent action of AtCCS52A isoforms in endoreduplication and plant size control. In: New Phytologist. 2013 ; Vol. 198, No. 4. pp. 1049-1059.
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