Comparison of photon with electron boost in treatment of early stage breast cancer

Arpad Kovacs, Janaki Hadjiev, Ferenc Lakosi, Csaba Glavak, Gergely Antal, P. Bogner, Akos Horvath, I. Repa

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In the treatment of early stage breast cancer breast conserving surgery (BCS) followed by whole breast irradiation (WBI) is a standard method. The impact of the tumor bed boost following WBI is well-defined, but there are various delivery methods. In this study the electron and the photon boost techniques were compared. For 78 early stage breast cancer patients both CT based 3D conformal photon boost and electron boost plans were created. For dosimetric comparison coverage index (CI), external volume index (EI) and conformality index (COIN) were studied. Lung volume receiving a dose of 2 Gy was also reviewed. Seventy-eight patients with 156 plans were compared. The mean tumor bed volume was measured as 61.39 cm3 the mean tumor bed-skin distance was 3.13 cm. In the case of CI and COIN significant differences were found in favor of the photon boost. In the comparison of EI no significant difference was detected between the two techniques. The mean lung volume receiving 2 Gy were 42.3 and 168.35 cm3, for photons and electrons respectively. In the adjuvant treatment of early stage breast cancer WBI followed by conformal photon boost showed to be superior to electron boost in focus of the COIN and CI.

Original languageEnglish
Pages (from-to)193-197
Number of pages5
JournalPathology and Oncology Research
Volume14
Issue number2
DOIs
Publication statusPublished - Jun 2008

Fingerprint

Photons
Electrons
Breast Neoplasms
Breast
Therapeutics
Lung
Segmental Mastectomy
Tumor Burden
Neoplasms
Skin

Keywords

  • Boost
  • Breast cancer
  • Electron
  • Photon
  • Radiotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Pathology and Forensic Medicine

Cite this

Comparison of photon with electron boost in treatment of early stage breast cancer. / Kovacs, Arpad; Hadjiev, Janaki; Lakosi, Ferenc; Glavak, Csaba; Antal, Gergely; Bogner, P.; Horvath, Akos; Repa, I.

In: Pathology and Oncology Research, Vol. 14, No. 2, 06.2008, p. 193-197.

Research output: Contribution to journalArticle

Kovacs, Arpad ; Hadjiev, Janaki ; Lakosi, Ferenc ; Glavak, Csaba ; Antal, Gergely ; Bogner, P. ; Horvath, Akos ; Repa, I. / Comparison of photon with electron boost in treatment of early stage breast cancer. In: Pathology and Oncology Research. 2008 ; Vol. 14, No. 2. pp. 193-197.
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