Comparison of Monte Carlo simulated and measured performance parameters of miniPET scanner

S. A. Kis, M. Emri, G. Opposits, T. Bükki, I. Valastyán, Gy Hegyesi, J. Imrek, G. Kalinka, J. Molnár, D. Novák, J. Végh, A. Kerek, L. Trón, L. Balkay

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In vivo imaging of small laboratory animals is a valuable tool in the development of new drugs. For this purpose, miniPET, an easy to scale modular small animal PET camera has been developed at our institutes. The system has four modules, which makes it possible to rotate the whole detector system around the axis of the field of view. Data collection and image reconstruction are performed using a data acquisition (DAQ) module with Ethernet communication facility and a computer cluster of commercial PCs. Performance tests were carried out to determine system parameters, such as energy resolution, sensitivity and noise equivalent count rate. A modified GEANT4-based GATE Monte Carlo software package was used to simulate PET data analogous to those of the performance measurements. GATE was run on a Linux cluster of 10 processors (64 bit, Xeon with 3.0 GHz) and controlled by a SUN grid engine. The application of this special computer cluster reduced the time necessary for the simulations by an order of magnitude. The simulated energy spectra, maximum rate of true coincidences and sensitivity of the camera were in good agreement with the measured parameters.

Original languageEnglish
Pages (from-to)449-452
Number of pages4
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume571
Issue number1-2 SPEC. ISS.
DOIs
Publication statusPublished - Feb 1 2007

Keywords

  • Monte Carlo simulation
  • Performance parameters
  • Small animal PET

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

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