Comparison of four serological tests for Borrelia burgdorferi in Bell's palsy

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Abstract

Four serological tests for Borrelia burgdorferi were compared in 117 Bell's palsy patients. Sera were tested against a whole cell sonicate by ELISA (SELISA), against a flagelles extract by ELISA (FELISA), traditional IFA and IFA after absorption with Treponema reiteri (ABIF). Altogether 35, 35, 29 and 20 cases were positive by IFA, FELISA, ABIF and SELISA, respectively. All 10 typical Bannwarth's syndrome cases were positive by IFA and ABIF, nine by FELISA, but only six by SELISA. In the 16 patients with concomitant erythema chronicum migrans (ECM), 15 proved to be positive by IFA, 12 by FELISA, 11 by ABIF and seven by SELISA. This data show that IFA may be one of the best routine laboratory indicators for borrelia infection.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalSerodiagnosis and Immunotherapy in Infectious Disease
Volume4
Issue number4
DOIs
Publication statusPublished - Aug 1990

Keywords

  • Lyme borreliosis
  • facial palsy
  • flagellum ELISA
  • immunofluorescence assay
  • serodiagnosis

ASJC Scopus subject areas

  • Immunology
  • Microbiology (medical)

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