A klinikai paraméterek változásai 1938-1951 es 1990-2002 között, a Debreceni Idegklinika agyboncolási adatainak elemzése alapján.

Translated title of the contribution: Comparison of clinical data of two autopsy series, 1938-1951 and 1990-2002, at the Debrecen University Department of Neurology

lldikó Szalma, Agnes Kiss, Zsolt Cselényi, Katalin Hegedus, L. Csiba

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

BACKGROUND: The clinical parameters of autopsied brains in two periods (1938-1951 and 1990-2002) were analyzed and compared. METHODS: Gender distribution, age, clinical diagnosis, treatment length of 695 (1938-1951) and 1378 (1990-2002) autopsies of Department of Neurology, Debrecen, Hungary were investigated. RESULT: Between 1938-1951 mean 49.6 +/- 15.5 autopsies/year were performed while in the 1990-2002 the autopsies raised to 106 +/- 19.6 /year. In the first period almost all deceased patient has been autopsied, but the ratio decreased on 68.9% between 1990-2002. The average age of autopsied patients (39.1 +/- 2.9 years) almost doubled after 40 years (69.5 +/- 2.0 years). In the first period (1938-1951) the infectious and tumorous cases were most frequent (33.6% and 31.2%), while in the second one, the cerebrovascular diseases dominated (84.5%). There was no significant difference between the treatment lengths of two periods (18.1 and 14.5 days, respectively). CONCLUSIONS: While the absolute number of autopsies raised after 40 years, the ratio decreased at our department (from 100% to 68.9%), similarly to the worldwide trends. The significantly higher age of autopsied patients and the different spectrum of clinical diagnosis reflects the decrease of infectious diseases and increase of stroke frequency and the ageing of the Hungarian population. Authors sustain with literary data that autopsy should not be ignored, and are convinced, together with professor Mohr, that "autopsy is the ultimate audit of medicine, the yardstick of clinical care and research. To dispence with autopsy is an unfortunate trend that certainly endangers the value of clinical research."

Original languageHungarian
Pages (from-to)1699-1704
Number of pages6
JournalOrvosi Hetilap
Volume145
Issue number33
Publication statusPublished - Aug 15 2004

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Neurology
Autopsy
Hospital Distribution Systems
Cerebrovascular Disorders
Hungary
Clinical Medicine
Age Distribution
Research
Communicable Diseases
Stroke
Brain
Therapeutics
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A klinikai paraméterek változásai 1938-1951 es 1990-2002 között, a Debreceni Idegklinika agyboncolási adatainak elemzése alapján. / Szalma, lldikó; Kiss, Agnes; Cselényi, Zsolt; Hegedus, Katalin; Csiba, L.

In: Orvosi Hetilap, Vol. 145, No. 33, 15.08.2004, p. 1699-1704.

Research output: Contribution to journalArticle

Szalma, lldikó ; Kiss, Agnes ; Cselényi, Zsolt ; Hegedus, Katalin ; Csiba, L. / A klinikai paraméterek változásai 1938-1951 es 1990-2002 között, a Debreceni Idegklinika agyboncolási adatainak elemzése alapján. In: Orvosi Hetilap. 2004 ; Vol. 145, No. 33. pp. 1699-1704.
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title = "A klinikai param{\'e}terek v{\'a}ltoz{\'a}sai 1938-1951 es 1990-2002 k{\"o}z{\"o}tt, a Debreceni Idegklinika agyboncol{\'a}si adatainak elemz{\'e}se alapj{\'a}n.",
abstract = "BACKGROUND: The clinical parameters of autopsied brains in two periods (1938-1951 and 1990-2002) were analyzed and compared. METHODS: Gender distribution, age, clinical diagnosis, treatment length of 695 (1938-1951) and 1378 (1990-2002) autopsies of Department of Neurology, Debrecen, Hungary were investigated. RESULT: Between 1938-1951 mean 49.6 +/- 15.5 autopsies/year were performed while in the 1990-2002 the autopsies raised to 106 +/- 19.6 /year. In the first period almost all deceased patient has been autopsied, but the ratio decreased on 68.9{\%} between 1990-2002. The average age of autopsied patients (39.1 +/- 2.9 years) almost doubled after 40 years (69.5 +/- 2.0 years). In the first period (1938-1951) the infectious and tumorous cases were most frequent (33.6{\%} and 31.2{\%}), while in the second one, the cerebrovascular diseases dominated (84.5{\%}). There was no significant difference between the treatment lengths of two periods (18.1 and 14.5 days, respectively). CONCLUSIONS: While the absolute number of autopsies raised after 40 years, the ratio decreased at our department (from 100{\%} to 68.9{\%}), similarly to the worldwide trends. The significantly higher age of autopsied patients and the different spectrum of clinical diagnosis reflects the decrease of infectious diseases and increase of stroke frequency and the ageing of the Hungarian population. Authors sustain with literary data that autopsy should not be ignored, and are convinced, together with professor Mohr, that {"}autopsy is the ultimate audit of medicine, the yardstick of clinical care and research. To dispence with autopsy is an unfortunate trend that certainly endangers the value of clinical research.{"}",
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T1 - A klinikai paraméterek változásai 1938-1951 es 1990-2002 között, a Debreceni Idegklinika agyboncolási adatainak elemzése alapján.

AU - Szalma, lldikó

AU - Kiss, Agnes

AU - Cselényi, Zsolt

AU - Hegedus, Katalin

AU - Csiba, L.

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Y1 - 2004/8/15

N2 - BACKGROUND: The clinical parameters of autopsied brains in two periods (1938-1951 and 1990-2002) were analyzed and compared. METHODS: Gender distribution, age, clinical diagnosis, treatment length of 695 (1938-1951) and 1378 (1990-2002) autopsies of Department of Neurology, Debrecen, Hungary were investigated. RESULT: Between 1938-1951 mean 49.6 +/- 15.5 autopsies/year were performed while in the 1990-2002 the autopsies raised to 106 +/- 19.6 /year. In the first period almost all deceased patient has been autopsied, but the ratio decreased on 68.9% between 1990-2002. The average age of autopsied patients (39.1 +/- 2.9 years) almost doubled after 40 years (69.5 +/- 2.0 years). In the first period (1938-1951) the infectious and tumorous cases were most frequent (33.6% and 31.2%), while in the second one, the cerebrovascular diseases dominated (84.5%). There was no significant difference between the treatment lengths of two periods (18.1 and 14.5 days, respectively). CONCLUSIONS: While the absolute number of autopsies raised after 40 years, the ratio decreased at our department (from 100% to 68.9%), similarly to the worldwide trends. The significantly higher age of autopsied patients and the different spectrum of clinical diagnosis reflects the decrease of infectious diseases and increase of stroke frequency and the ageing of the Hungarian population. Authors sustain with literary data that autopsy should not be ignored, and are convinced, together with professor Mohr, that "autopsy is the ultimate audit of medicine, the yardstick of clinical care and research. To dispence with autopsy is an unfortunate trend that certainly endangers the value of clinical research."

AB - BACKGROUND: The clinical parameters of autopsied brains in two periods (1938-1951 and 1990-2002) were analyzed and compared. METHODS: Gender distribution, age, clinical diagnosis, treatment length of 695 (1938-1951) and 1378 (1990-2002) autopsies of Department of Neurology, Debrecen, Hungary were investigated. RESULT: Between 1938-1951 mean 49.6 +/- 15.5 autopsies/year were performed while in the 1990-2002 the autopsies raised to 106 +/- 19.6 /year. In the first period almost all deceased patient has been autopsied, but the ratio decreased on 68.9% between 1990-2002. The average age of autopsied patients (39.1 +/- 2.9 years) almost doubled after 40 years (69.5 +/- 2.0 years). In the first period (1938-1951) the infectious and tumorous cases were most frequent (33.6% and 31.2%), while in the second one, the cerebrovascular diseases dominated (84.5%). There was no significant difference between the treatment lengths of two periods (18.1 and 14.5 days, respectively). CONCLUSIONS: While the absolute number of autopsies raised after 40 years, the ratio decreased at our department (from 100% to 68.9%), similarly to the worldwide trends. The significantly higher age of autopsied patients and the different spectrum of clinical diagnosis reflects the decrease of infectious diseases and increase of stroke frequency and the ageing of the Hungarian population. Authors sustain with literary data that autopsy should not be ignored, and are convinced, together with professor Mohr, that "autopsy is the ultimate audit of medicine, the yardstick of clinical care and research. To dispence with autopsy is an unfortunate trend that certainly endangers the value of clinical research."

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