The aldehyde-bisulfite-toluidine blue (ABT) reaction is a selective topo-optical test of vicinal-OH and amino-OH groups. The localization of cardiac glycoside was investigated morphologically. After digoxin the sarcolemma membranes, capillaries and sinus node showed strong basophilia and negative birefringence. The topo-optical reaction are useful for the histopathological examination. The new method gives the possibility to the digoxin intoxication with a high specificity.
- Digoxin poisoning
- Glycoside localization, topo-optical reaction
- Poisoning, digoxin
ASJC Scopus subject areas
- Pathology and Forensic Medicine