Comparative topo-optical investigation of cardiac glycoside localization

P. Sótónyi, E. Somogyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The aldehyde-bisulfite-toluidine blue (ABT) reaction is a selective topo-optical test of vicinal-OH and amino-OH groups. The localization of cardiac glycoside was investigated morphologically. After digoxin the sarcolemma membranes, capillaries and sinus node showed strong basophilia and negative birefringence. The topo-optical reaction are useful for the histopathological examination. The new method gives the possibility to the digoxin intoxication with a high specificity.

Original languageEnglish
Pages (from-to)87-94
Number of pages8
JournalZeitschrift für Rechtsmedizin
Volume90
Issue number2
DOIs
Publication statusPublished - Jul 1983

Fingerprint

Cardiac Glycosides
Digoxin
Birefringence
Tolonium Chloride
Sarcolemma
Sinoatrial Node
intoxication
Aldehydes
examination
Membranes
Group
hydrogen sulfite

Keywords

  • Digoxin poisoning
  • Glycoside localization, topo-optical reaction
  • Poisoning, digoxin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Anatomy

Cite this

Comparative topo-optical investigation of cardiac glycoside localization. / Sótónyi, P.; Somogyi, E.

In: Zeitschrift für Rechtsmedizin, Vol. 90, No. 2, 07.1983, p. 87-94.

Research output: Contribution to journalArticle

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