Comparative topo-optical investigation of cardiac glycoside localization

P. Sótonyi, E. Somogyi

Research output: Contribution to journalArticle

2 Citations (Scopus)


The aldehyde-bisulfite-toluidine blue (ABT) reaction is a selective topo-optical test of vicinal-OH and amino-OH groups. The localization of cardiac glycoside was investigated morphologically. After digoxin the sarcolemma membranes, capillaries and sinus node showed strong basophilia and negative birefringence. The topo-optical reaction are useful for the histopathological examination. The new method gives the possibility to the digoxin intoxication with a high specificity.

Original languageEnglish
Pages (from-to)87-94
Number of pages8
JournalZeitschrift für Rechtsmedizin
Issue number2
Publication statusPublished - Jul 1 1983



  • Digoxin poisoning
  • Glycoside localization, topo-optical reaction
  • Poisoning, digoxin

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

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