Comparative study of enzyme-linked immunosorbent assay and radioimmunoassay techniques in determining serum placental protein 14 levels in gynecologic patients

L. A. Scherbakova, P. M. Göcze, G. A. Olefirenko, G. N. Than, D. G. Szabò, D. D. Petrunin, Yu S. Tatarinov, I. F. Csaba

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Abstract

A comparative analysis of radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) techniques in determining placental protein 14 (PP14) levels in gynecologic patients was performed. Serum PP14 levels were assessed in the patients in the last period of gestation, during menopause and in healthy nonpregnant controls. The possible discrepancy in PPM levels was also examined in gynecologic patients with benign and malignant tumors. Both RIA and ELISA techniques proved to be sufficiently sensitive to measure PPM concentration.

Original languageEnglish
Pages (from-to)267-271
Number of pages5
JournalTumor Biology
Volume12
Issue number5
DOIs
Publication statusPublished - 1991

Keywords

  • Enzyme-linked immunosorbent assay
  • Placental protein 14
  • Radioimmunoassay

ASJC Scopus subject areas

  • Cancer Research

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    Scherbakova, L. A., Göcze, P. M., Olefirenko, G. A., Than, G. N., Szabò, D. G., Petrunin, D. D., Tatarinov, Y. S., & Csaba, I. F. (1991). Comparative study of enzyme-linked immunosorbent assay and radioimmunoassay techniques in determining serum placental protein 14 levels in gynecologic patients. Tumor Biology, 12(5), 267-271. https://doi.org/10.1159/000217714